Optical touch pointer for fluorescence guided glioblastoma resection using 5-aminolevulinic acid

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Optical touch pointer for fluorescence guided glioblastoma resection using 5-aminolevulinic acid.

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The need for novel, effective, and safe treatments for malignant glioma is obvious. Despite surgery, radiotherapy, and chemotherapy, the median survival time of patients with glioblastoma multiforme (World Health Organization Grade IV) still does not exceed 15 months. Patients with anaplastic astrocytoma (World Health Organization Grade III) have a slightly better prognosis. As a result of the ...

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BACKGROUND Resection guided by 5-aminolevulinic acid (5-ALA) fluorescence has proved to be useful in intracranial glioma surgery. However, the effects of 5-ALA on spinal cord tumors remain unknown. OBJECTIVE To evaluate the usefulness of 5-ALA fluorescence-guided resection of intramedullary ependymoma for achieving maximum tumor resection. METHODS This study included 10 patients who underwe...

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ژورنال

عنوان ژورنال: Lasers in Surgery and Medicine

سال: 2010

ISSN: 0196-8092

DOI: 10.1002/lsm.20868